Tricine
SIGMA/RES3077T-A7
Synonym: Tricine; N-
CAS Number: 5704-04-1
Empirical Formula (Hill Notation): C6H13NO5
Molecular Weight: 179.17
EC Number: 227-193-6
MDL Number: MFCD00004277
Linear Formula: (HOCH2)3CNHCH2CO2H
Product Type: Chemical
| biological source | synthetic |
| foreign activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| form | powder |
| impurities | Endotoxin, microbial, and trace metals; tested |
| InChI | 1S/C6H13NO5/c8-2-6(3-9,4- |
| InChI key | SEQKRHFRPICQDD-UHFFFAOYSA |
| pKa (25 °C) | 8.1 |
| Quality Level | 400 ![]() |
| SMILES string | OCC(CO)(CO)NCC(O)=O |
| suitability | suitable for manufacturing use |
| technique(s) | cell culture | mammalian: suitable |
| useful pH range | 7.4-8.8 |
| Application: | Buffer component for separation of low molecular weight peptides. |
| Application: | Tricine is a biological buffer often referred to as a “Good’s” buffer. The pKa of Tricine is 8.1 which makes Tricine is a good candidate for biological applications that require pH control above physiological. Tricine is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity. Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program ![]() Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step. Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | Product is available in the following package sizes: RES3077T-A701X: 100 gm container RES3077T-A702X: 1 kg container RES3077T-A704X: 10 kg container RES3077T-A705X: 25 kg container |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12161700 |

