Tromethamine
SIGMA/RES3193T-A7
Synonym: Tromethamine; Tris
CAS Number: 77-86-1
Empirical Formula (Hill Notation): C4H11NO3
Molecular Weight: 121.14
EC Number: 201-064-4
MDL Number: MFCD00004679
Linear Formula: C4H11NO3
Product Type: Chemical
Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.
| biological source | synthetic |
| foreign activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| form | powder |
| impurities | Endotoxin, microbial, and heavy metals; tested |
| InChI | 1S/C4H11NO3/c5-4(1-6,2-7) |
| InChI key | LENZDBCJOHFCAS-UHFFFAOYSA |
| Quality Level | 400  |
| SMILES string | NC(CO)(CO)CO |
| suitability | suitable for manufacturing use |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Tromethamine is a commonly used biological buffer which is also referred to as Tris or Trizma. Tris as a buffer has very broad usage in diagnostics and downstream purifications. The pKa of Tris is 7.77 which corresponds closely to a physiological pH of 7.36. Tromethamine is used in biopharmaceutical buffer formulations (both upstream and downstream), electrophoresis separations and diagnostic reagent formulations. Tromethamine is especially useful in downstream purification processes. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step. Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | Product is available in the following package sizes: RES3193T-A701X: 100 gm container RES3193T-A703X: 5 kg container RES3193T-A705X: 25 kg container RES3193T-A706X: 50 kg container |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352116 |