HEPES sodium salt
SIGMA/RES6007H-A7
Synonym: 4-
CAS Number: 75277-39-3
Empirical Formula (Hill Notation): C8H17N2NaO4S
Molecular Weight: 260.29
EC Number: 278-169-7
MDL Number: MFCD00036463
Linear Formula: C8H17N2NaO4S
Product Type: Chemical
| biological source | synthetic |
| foreign activity | Cytotoxicity, DNase, NICKase, RNase, and Protease; tested |
| form | powder |
| impurities | Endotoxin, microbial, and trace metals; tested |
| InChI | 1S/C8H18N2O4S.Na/c11-7-5- |
| InChI key | RDZTWEVXRGYCFV-UHFFFAOYSA |
| pKa (25 °C) | 7.5 |
| Quality Level | 400 ![]() |
| SMILES string | [Na+].OCCN1CCN(CC1)CCS([O |
| suitability | suitable for manufacturing use |
| technique(s) | cell culture | mammalian: suitable |
| useful pH range | 6.8-8.2 |
| Application: | HEPES Sodium is a biological buffer often referred to as a “Good’s” buffer. HEPES Sodium, used in conjunction with HEPES, is the most commonly used biological buffer formulation since the pKa of the buffer is 7.31 which corresponds to the physiological pH of 7.36. HEPES Sodium is considered to be non-toxic to culture cell lines, highly water soluble and provides high-solution clarity. HEPES Sodium is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream) and diagnostic reagent formulations. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program ![]() Buffer quality is vital for the success of biopharmaceutical processes, because buffers are indispensable in nearly every production step. Our broad portfolio of buffer materials manufactured under appropriate controls is tailored to your needs. Ranging from non-GMP grades for low-risk application, to IPEC-PQG GMP for higher-risk applications, we have products covering all your manufacturing needs. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | The product is available in the following package sizes: RES6007H-A701X: 100g container RES6007H-A702X: 1kg container RES6007H-A704X: 10kg container RES6007H-A705X: 25kg container |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12161700 |

