Ketanserin (+)-tartrate salt

SIGMA/S006 - ≥97%, solid

Synonym: 3-(2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl)-2,4(1H,3H)-quinazolinedione (+)-tartrate salt; R 41468 (+)-tartrate salt

CAS Number: 83846-83-7
Empirical Formula (Hill Notation): C₂₂H₂₂FN₃O₃ · C₄H₆O₆
Molecular Weight: 545.51
EC Number: 281-062-8
MDL Number: MFCD00084651
Linear Formula: C₂₂H₂₂FN₃O₃ · C₄H₆O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-S006-10MG	10 mg	$90.10 1/EA	Add To Favorites
45-S006-50MG	50 mg	$287.00 1/EA	Add To Favorites
45-S006-250MG	250 mg	$1030.00 1/EA	Add To Favorites
45-S006-500MG	500 mg	$1710.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S006-250MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97%
color	white
form	solid
InChI	1S/C22H22FN3O3.C4H6O6/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29;5-1(3(7)8)2(6)4(9)10/h1-8,16H,9-14H2,(H,24,29);1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
InChI key	KMTLTEVOQLMYRS-LREBCSMRSA-N
Quality Level	100
SMILES string	O[C@H]([C@@H](O)C(O)=O)C(O)=O.Fc1ccc(cc1)C(=O)C2CCN(CC2)CCN3C(=O)Nc4ccccc4C3=O
solubility	0.1 M HCl: 6 mg/mL (lit.)(lit.)
	DMSO: 52 mg/mL (lit.)(lit.)
	ethanol: 3 mg/mL
storage temp.	2-8°C

Application:	Ketanserin (+)-tartrate salt has been used: • as a 5HT2A antagonist in Krebs-Henseleit buffer solution • for hormonal treatment to study the effects of exogenous manipulation of different hormonal systems in interaction with parasite infection on client′s behavior • to study the behavioural changes of incision pain rats
Biochem/physiol Actions:	Ketanserin stimulates collagen synthesis and is involved in wound healing.
Biochem/physiol Actions:	Selective 5-HT₂ serotonin receptor antagonist.
Biochem/physiol Actions:	Selective 5-HT₂ serotonin receptor antagonist. Ketanserin significantly reduces nicotine self-administration in rats, supporting an unexpected involvement of serotonin in nicotine addiction.
Packaging:	10, 50 mg in glass bottle
Packaging:	250, 500 mg in poly bottle

Symbol	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301 + P310
Hazard Codes	T
Risk Statements	25
Safety Statements	22-36/37/39-45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97%
Storage Temp.	2-8°C
UNSPSC	12352202

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