Spermidine
SIGMA/S0266 - BioReagent, Molecular Biology, suitable for cell culture, ≥98%
Synonym: 1,8-
CAS Number: 124-20-9
Empirical Formula (Hill Notation): C7H19N3
Molecular Weight: 145.25
EC Number: 204-689-0
MDL Number: MFCD00008229
Linear Formula: NH2(CH2)3NH(CH2)4NH2
Product Type: Chemical
| assay | ≥98% |
| density | 0.925 g/mL at 25 °C (lit.) |
| foreign activity | DNase, RNase, and protease, none detected |
| form | solid or liquid |
| grade | Molecular Biology |
| InChI | 1S/C7H19N3/c8-4-1-2-6-10- |
| InChI key | ATHGHQPFGPMSJY-UHFFFAOYSA |
| mol wt | 145.25 (AMU) |
| product line | BioReagent |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | NCCCCNCCCN |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Spermidine has been used in the preparation of gold beads and as a component in nuclei isolation buffer (NIB). |
| Application: | Spermidine is suitable for use in molecular biology buffers and for precipitation of DNA >100 bp in length. It was used to deliver DNA in plants and mammalian cells by particle bombardment technique. |
| Biochem/physiol Actions: | Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T4 polynucleotide kinase activity. |
| Biochem/physiol Actions: | Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T4 polynucleotide kinase activity. |
| Biochem/physiol Actions: | Spermidine helps to maintain the proper activity of gene expression. This polyamine plays a key role in intermediate metabolism. It also serves as an inhibitor of the acetyl transferase activity of E1A-associated protein p300 (EP300). Spermidine participates in cell growth. |
| Disclaimer: | Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently. |
| General description: | Spermidine belongs to the natural polyamines, that are found in chloroplasts and in bacterial or eukaryotic cells. |
| Symbol | GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338 + P310 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-36/37/39-45 |
| RIDADR | UN 3259PSN2 8 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 233.6 °F - closed cup |
| Flash Point(C) | 112 °C - closed cup |
| Purity | ≥98% |
| Density | 0.925 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |


