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Sulfameter

SIGMA/S0383

Synonym: 5-Methoxysulfadiazine; N1-(5-Methoxypyrimidin-2-yl)sulfanilamide; Sulfamethoxydiazine

CAS Number: 651-06-9
Empirical Formula (Hill Notation): C11H12N4O3S
Molecular Weight: 280.30
EC Number: 211-480-8
MDL Number: MFCD00006067
Linear Formula: C11H12N4O3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S0383-5G 5 g
 $104.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S0383-5G

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
  mycobacteria
  parasites
color white to faint yellow
form powder
InChI 1S/C11H12N4O3S/c1-18-9-6-13-11(14-7-9)15-19(16,17)10-4-2-8(12)3-5-10/h2-7H,12H2,1H3,(H,13,14,15)
InChI key GPTONYMQFTZPKC-UHFFFAOYSA-N
mode of action enzyme | inhibits
Quality Level 200 
SMILES string COc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1
storage condition (Keep container tightly closed in a dry and well-ventilated place. Light sensitive.)
storage temp. 2-8°C
Application: Sulfameter is a sulfonamide antibiotic used as a leprostatic agent and to treat urinary tract infections. It has been investigated as a potential therapy for chloroquine-resistant malaria during pregnancy.
Biochem/physiol Actions: Sulfameter is a sulfonamide antibiotic. Sulfonamides block the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfonamides are competitive inhibitors of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. Sulfameter is a dihydrofolate reductase (DHFR) inhibitor. Sulfonamides are active against Gram positive bacteria and Gram negative bacteria. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
General description: Chemical structure: sulfonamide
Other Notes: Keep container tightly closed in a dry and well-ventilated place. Light sensitive.
Packaging: 5 g in poly bottle
Storage Temp. 2-8°C
UNSPSC 51283913

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