Anti-Sodium Channel PN4 antibody produced in rabbit
SIGMA/S0438 - affinity isolated antibody, lyophilized powder
Synonym: Anti-Sodium Channel Scn8a
MDL Number: MFCD03455989
Product Type: Chemical
Immunohistochemistry Anti-Nav1.6: Cat. No. S0438: Immunohistochemical staining of Mouse hippocampus using Anti-Nav1.6 antibody. A. Nav1.6 (green) is robustly expressed in the CA1 pyramidal layer (white arrows). B. Staining with Mouse Anti-Parvalbumin (red), a marker of interneurons. C. merged image of panels A and B reveals that Nav1.6 appears in some interneurons (arrow) but is not restricted to interneurons. DAPI is used as the counterstain.
Immunocytochemistry Anti-Nav1.6: Cat. No. S0438: Immunocytochemical staining of paraformaldehyde-fixed and permeabilized DRG primary culture. A. Staining using Anti-Nav1.6 antibody, (1:200) followed by Goat Anti-Rabbit-AlexaFluor-555 secondary antibody. B. Nuclear staining using the cell-permeable dye Hoechst 33342. C. Merged image of panels A and B
Immunoblotting Anti-NaV1.6: Cat. No. S0438: Western blot analysis of Rat brain membrane. Lanes 1. Anti-NaV1.6 antibody, (1:200). 2. Anti-NaV1.6 antibody, preincubated with the control peptide antigen.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | rat |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot (chemiluminescent): 1:200 |
| UniProt accession no. | O88420  |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | synthetic peptide corresponding to residues 1042-1061 of mouse or rat Scn8a (intracellular epitope). The peptide is highly homologous (19/20 residues identical) in human. |
| Physical form: | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide. |
| Symbol |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 + H332 - H311 - H411 |
| Precautionary statements | P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 |
| Hazard Codes | T,N |
| Risk Statements | 24/25-51/53 |
| Safety Statements | 36/37-45-61 |
| RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |