SB-366791

SIGMA/S0441 - ≥98% (HPLC), powder

Synonym: N-(3-Methoxyphenyl)-4-chlorocinnamide

CAS Number: 472981-92-3
Empirical Formula (Hill Notation): C₁₆H₁₄NO₂Cl
Molecular Weight: 287.74
MDL Number: MFCD01033818
Linear Formula: C₁₆H₁₄NO₂Cl
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-S0441-5MG	5 mg	$227.00 1/EA		Add To Favorites
45-S0441-25MG	25 mg	$897.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	white to beige
form	powder
InChI	1S/C16H14ClNO2/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+
InChI key	RYAMDQKWNKKFHD-JXMROGBWSA-N
originator	GlaxoSmithKline
Quality Level	200
SMILES string	COc1cccc(NC(=O)C=Cc2ccc(Cl)cc2)c1
solubility	DMSO: 5 mg/mL, clear

Application:	SB-366791 has been used as a transient receptor potential cation channel subfamily V member 1 (TRPV1) antagonist: • to infer the in vitro and in vivo pharmacology of (E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acrylamide (AMG 9810) • to study its effects on sodium hydrogen sulfide (NaHS) or capsaicin-induced contractile activity • to study the inhibitory potency of phoneutria toxin (PnTx3-5) (native and recombinant) on various responses mediated by transient receptor potential cation channel subfamily V member 1 (TRPV1)
Biochem/physiol Actions:	SB-366791 might exhibit analgesic properties on bone cancer-related pain behavior.
Biochem/physiol Actions:	Vanilloid receptor-1 (TRPV1) antagonist.
Features and Benefits:	This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging:	5 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
UNSPSC	12352200

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