Streptokinase C from Streptococcus sp.
SIGMA/S0577 - lyophilized solid, ≥3,500 unit/mg solid
Synonym: Streptokinase
Product Type: Chemical
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| application(s) | life science and biopharma |
| assay | 40—60% protein (biuret) |
| biological source | bacterial (Streptococcus sp.) |
| color | off-white to light yellow |
| form | lyophilized solid |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| specific activity | ≥3,500 unit/mg solid |
| storage temp. | −20°C |
| Application: | Streptokinase C from Streptococcus sp. has been used to quantitate the survival of Staphylococcus aureus in whole human blood. |
| Biochem/physiol Actions: | Streptokinase shows fibrinolytic activity by triggering the circulatory plasminogen either via a fibrin-dependent or fibrin-independent mechanism. Streptokinase has been studied majorly in terms of its therapeutic efficacy and treating myocardial infarction to dissolve clots. |
| General description: | Research area: Cell Signaling Streptokinase is an extracellular enzyme, a single-chain polypeptide produced by several strains of β-hemolytic Streptococci. It is composed of multiple structural domains like α-, β-, and γ-domains that are involved in various functions. |
| Other Notes: | One unit will liquify a standard clot of fibrinogen, plasminogen, and thrombin at pH 7.5 at 37 °C in 10 min. |
| Packaging: | 10000, 50000 units in glass bottle |
| Physical form: | Lyophilized powder containing approx. 50% bovine serum albumin (total protein by biuret) with sodium glutamate. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 40—60% protein (biuret) |
| activity | specific activity: ≥3,500 unit/mg solid |
| Storage Temp. | −20°C |
| Enzyme Commission (EC) Number | 3.4.99.0 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |