Sulfaphenazole
SIGMA/S0758 - ≥98%
Synonym: 4-
CAS Number: 526-08-9
Empirical Formula (Hill Notation): C15H14N4O2S
Molecular Weight: 314.36
EC Number: 208-384-3
MDL Number: MFCD00057226
Linear Formula: C15H14N4O2S
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S0758-1G
| assay | ≥98% |
| form | powder |
| InChI | 1S/C15H14N4O2S/c16-12-6-8 |
| InChI key | QWCJHSGMANYXCW-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Nc1ccc(cc1)S(=O)(=O)Nc2cc |
| solubility | ethanol: 25 mg/mL, clear, colorless to yellow |
| storage temp. | 2-8°C |
| Application: | Sulfaphenazole has been used as a positive control to inhibit cytochrome P450 2C9 (cyp2c9) to quantify Rhodiola rosea inhibition. It has also been used as cytochrome P450 2C9 (cyp2c9) inhibitor in endothelial cells and microsomal preparations. |
| Biochem/physiol Actions: | Antibacterial. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Specific inhibitor of CYP2C9. Blocks pro-inflammatory and atherogenic effects of linoleic acid (increase in oxidative stress and activation of AP-1) mediated by CYP2C9. Inhibits bradykinin-induced tPA release. |
| Packaging: | 1 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352204 |