Saclofen
SIGMA/S166 - solid
Synonym: β-(Aminomethyl)-4-chlorobenzeneethanesulfonic acid
CAS Number: 125464-42-8
Empirical Formula (Hill Notation): C9H12ClNO3S
Molecular Weight: 249.71
MDL Number: MFCD00216817
Linear Formula: C9H12ClNO3S
Product Type: Chemical
| color | white |
| form | solid |
| InChI | 1S/C9H12ClNO3S/c10-9-3-1- |
| InChI key | JYLNVJYYQQXNEK-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | NCC(CS(O)(=O)=O)c1ccc(Cl) |
| solubility | 0.1 M NaOH: 20 mg/mL |
| Application: | Saclofen has been used as a GABAB receptor antagonist to study the analgesic effect of repeated injections of oxycodone in rats. |
| Application: | Saclofen has been used to prevent the inhibitory action of oxytocin on capsaicin-induced glutamatergic spontaneous excitatory transmission in rat neurons. |
| Biochem/physiol Actions: | Saclofen is the sulphonic analog of baclofen and is a selective GABAB receptor antagonist. |
| Biochem/physiol Actions: | Saclofen might possess sympathetic nervous system-dependent anti-inflammatory action. |
| Packaging: | 5 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 51111800 |

