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SR 57227A

SIGMA/S1688 - solid

Synonym: 4-amino-1-(6-chloro-2-pyridyl)-piperidine hydrochloride

CAS Number: 77145-61-0
Empirical Formula (Hill Notation): C10H14ClN3 · HCl
Molecular Weight: 248.15
MDL Number: MFCD01756430
Linear Formula: C10H14ClN3 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S1688-5MG 5 mg
 $206.00
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color white
form solid
InChI 1S/C10H14ClN3.ClH/c11-9-2-1-3-10(13-9)14-6-4-8(12)5-7-14;/h1-3,8H,4-7,12H2;1H
InChI key FUMINTAAUJUVMP-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.NC1CCN(CC1)c2cccc(Cl)n2
solubility H2O: soluble 9 mg/mL
Application: SR 57227A may be used in 5-HT3-mediated cell signaling studies.
Biochem/physiol Actions: Potent and selective 5-HT3 serotonin receptor agonist.
Biochem/physiol Actions: SR 57227A is a highly selective of central and peripheral 5-HT3 receptors and an inhibitor of NMDA receptor-mediated responses in rat cortical pyramidal cells. It exhibits anti-depressant like effects in rats and decreased isolation-induced aggressive behavior.
Packaging: 5 mg in glass bottle
UNSPSC 12352200

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