Somatostatin

SIGMA/S1763 - powder, BioReagent, suitable for cell culture

Synonym: Growth hormone release inhibiting factor; SRIF; Somatostatin-14; Somatotropin release inhibiting factor

CAS Number: 38916-34-6
Empirical Formula (Hill Notation): C₇₆H₁₀₄N₁₈O₁₉S₂
Molecular Weight: 1637.88
EC Number: 254-186-5
MDL Number: MFCD00076762
Linear Formula: C₇₆H₁₀₄N₁₈O₁₉S₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-S1763-.1MG	0.1 mg	$63.60 1/EA	Add To Favorites
45-S1763-1MG	1 mg	$305.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
biological source	synthetic (organic)
form	powder
InChI	1S/C76H104N18O19S2/c1-41(79)64(100)82-37-61(99)83-58-39-114-115-40-59(76(112)113)92-72(108)57(38-95)91-75(111)63(43(3)97)94-71(107)54(33-46-23-11-6-12-24-46)90-74(110)62(42(2)96)93-66(102)51(28-16-18-30-78)84-69(105)55(34-47-36-81-49-26-14-13-25-48(47)49)88-68(104)53(32-45-21-9-5-10-22-45)86-67(103)52(31-44-19-7-4-8-20-44)87-70(106)56(35-60(80)98)89-65(101)50(85-73(58)109)27-15-17-29-77/h4-14,19-26,36,41-43,50-59,62-63,81,95-97H,15-18,27-35,37-40,77-79H2,1-3H3,(H2,80,98)(H,82,100)(H,83,99)(H,84,105)(H,85,109)(H,86,103)(H,87,106)(H,88,104)(H,89,101)(H,90,110)(H,91,111)(H,92,108)(H,93,102)(H,94,107)(H,112,113)/t41-,42+,43+,50-,51-,52-,53-,54-,55-,56-,57?,58-,59-,62-,63-/m0/s1
InChI key	NHXLMOGPVYXJNR-FQSIDJEASA-N
product line	BioReagent
Quality Level	200
shipped in	ambient
SMILES string	[H]N1[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](Cc4c[nH]c5ccccc45)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc6ccccc6)C(=O)N[C@@H]([C@@H](C)O)C(=O)NC(CO)C(=O)N[C@@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](C)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C1=O)C(O)=O
solubility	H₂O: 1 mg/mL
storage temp.	−20°C
technique(s)	cell culture \| mammalian: suitable

Amino Acid Sequence:	Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys
Application:	Somatostatin has been used in cell culture. It has also been used in the study of glucose-6-phosphate dehydrogenase activity in monolayer cultures of thyroid epithelial cells.
Biochem/physiol Actions:	Somatostatin regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin (SST) is a peptide. It performs several functions like anti-proliferation, pro-apoptosis and anti-migration. Somatostatin performs physiological activities with the help of various G protein-coupled receptor subtypes (SST receptor (SSTR)-1, SSTR2A, SSTR2B, and SSTR3–5).
Physical form:	powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
Preparation Note:	To prepare 2 μg/ml stock solution, dissolve in 5 ml sterile culture medium per μg somatostatin.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352209

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