Supercinnamaldehyde

SIGMA/S3322 - ≥98% (HPLC)

Synonym: 1,3-Dihydro-1-methyl-3-(2-oxopropylidene)-2H-Indol-2-one

CAS Number: 70351-51-8
Empirical Formula (Hill Notation): C₁₂H₁₁NO₂
Molecular Weight: 201.22
MDL Number: MFCD08530327
Linear Formula: C₁₂H₁₁NO₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-S3322-5MG	5 mg	$180.00 1/EA		Add To Favorites
45-S3322-25MG	25 mg	$811.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	faintly red to very dark red
form	powder
InChI	1S/C12H11NO2/c1-8(14)7-10-9-5-3-4-6-11(9)13(2)12(10)15/h3-7H,1-2H3/b10-7+
InChI key	CZKBLHCEDVWPRN-JXMROGBWSA-N
Quality Level	200
SMILES string	CN1C(=O)C(=CC(C)=O)c2ccccc12
solubility	DMSO: 10 mg/mL, clear
storage temp.	2-8°C

Application:	Supercinnamaldehyde may be used in transient receptor potential ankyrin 1 (TRPA 1)-mediated cell signaling studies.
Biochem/physiol Actions:	Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator. EC₅₀= 0.8 μM.
Biochem/physiol Actions:	Supercinnamaldehyde is a transient receptor potential ankyrin 1 (TRPA1) activator; EC₅₀ = 0.8 μM; derivative of cinnamaldehyde; covalently binds to and activates TRPA1 receptor (expressed in nociceptive neurons) by modifying its cysteine residues. Covalent modification of reactive cysteines within TRPA1 can cause channel activation, rapidly signaling potential tissue damage through the pain pathway.
Disclaimer:	Air-sensitive
Packaging:	5, 25 mg in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38-52/53
Safety Statements	26-36/37-61
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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