Advanced Search



SEW2871

SIGMA/S3944 - ≥98% (HPLC), solid

Synonym: 5-[4-Phenyl-5-(trifluoromethyl)-2-thienyl]-3-[3-(trifluoromethyl)phenyl]- 1,2,4-oxadiazole

CAS Number: 256414-75-2
Empirical Formula (Hill Notation): C20H10F6N2OS
Molecular Weight: 440.36
MDL Number: MFCD00096600
Linear Formula: C20H10F6N2OS
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S3944-1MG 1 mg
 $289.00
1/EA		 Add To Favorites
45-S3944-5MG 5 mg
 $1100.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white
form solid
InChI 1S/C20H10F6N2OS/c21-19(22,23)13-8-4-7-12(9-13)17-27-18(29-28-17)15-10-14(11-5-2-1-3-6-11)16(30-15)20(24,25)26/h1-10H
InChI key OYMNPJXKQVTQTR-UHFFFAOYSA-N
mp 94.5-95.3 °C
Quality Level 100 
SMILES string FC(F)(F)c1cccc(c1)-c2noc(n2)-c3cc(-c4ccccc4)c(s3)C(F)(F)F
solubility DMSO: ≥10 mg/mL
  H2O: insoluble
storage condition protect from light
storage temp. 2-8°C
Application: SEW2871 has been used as a sphingosine-1 phosphate (S1P) receptor agonist to determine the effects of reconstituting plasma apolipoprotein M (ApoM) /S1P on vascular permeability in mice.
Application: SEW2871 was used to mimic the effects of sphingosine-1 phosphate in HUVECs to study the innate immunity rendered by long pentraxin 3.
Biochem/physiol Actions: Novel, selective human sphingosine-1-phosphate subtype 1 (S1P1) receptor agonist.
Biochem/physiol Actions: SEW2871 is a selective agonist of spingosine-1 phosphate receptor. It exacerbates reperfusion arrhythmias by significantly prolonging the duration of ventricular tachycardia and ventricular fibrillation. SEW2871 modulates inflammatory reactions by influencing lymphocyte homing and cell migration. By the inhibition of proinflammatory molecules, SEW2871 reduces acute renal failure due to ischemia.
Features and Benefits: This compound is featured on the Lysophospholipid Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 1, 5 mg in glass bottle
Packaging: Light sensitive.
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Purity ≥98% (HPLC)
mp 94.5-95.3 °C
Storage Temp. 2-8°C
UNSPSC 12352211

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top