Semustine
SIGMA/S4026
Synonym: N-(2-Chloroethyl)-N′-(4-methylcyclohexyl)-N-nitrosourea; Methyl-CCNU
CAS Number: 13909-09-6
Empirical Formula (Hill Notation): C10H18ClN3O2
Molecular Weight: 247.72
MDL Number: MFCD00133811
Linear Formula: C10H18ClN3O2
Product Type: Chemical
| InChI | 1S/C10H18ClN3O2/c1-8-2-4- |
| InChI key | FVLVBPDQNARYJU-UHFFFAOYSA |
| SMILES string | CC1CCC(CC1)NC(=O)N(CCCl)N |
| Application: | Commonly used in pharmacological studies involving: • Nutrient-sensitized screening for drugs that shift the energy metabolism from mitchondrial respiration to glycolysis • CEOP regimen with semustine used as induction chemotherapy in patients with lymphoma • Investigations into its use for chemotherapy |
| Packaging: | 100 mg in poly bottle |
| Symbol | ![]() GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300 - H311 + H331 - H315 - H319 - H335 - H350 - H360 |
| Precautionary statements | P201 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 45-46-23/24/25-36/37/38 |
| Safety Statements | 53-22-26-36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352100 |


