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Saponin from Quillaja sp.

SIGMA/S4521 - Sapogenin content 20-35 %

CAS Number: 8047-15-2
EC Number: 232-462-6
MDL Number: MFCD00081981
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S4521-10G 10 g
 $69.70
1/EA		 Add To Favorites
45-S4521-25G 25 g
 $141.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S4521-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S4521-25G

 

composition Sapogenin content, 20-35%
description non-ionic
InChI 1S/C55H86O24/c1-10-23(2)46(71)79-43-44(72-24(3)60)55(22-59)26(17-50(43,4)5)25-11-12-30-51(6)15-14-32(52(7,21-58)29(51)13-16-53(30,8)54(25,9)18-31(55)61)75-49-41(77-48-38(67)36(65)34(63)28(20-57)74-48)39(68)40(42(78-49)45(69)70)76-47-37(66)35(64)33(62)27(1
InChI key AXNVHPCVMSNXNP-ZELRDNAQSA-N
Quality Level 300 
SMILES string O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@H]2[C@@H](O[C@@H]([C@H]([C@@H]2O)O[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)CO)C(=O)O)O[C@@H]3[C@@](C4[C@@](C5[C@]([C@@]6(C[C@H]([C@]7([C@H]([C@@H](C(CC7C6=CC5)(C)C)OC(=O)C(=C/C)C)OC(=O)C)CO)O)C)(CC4)C)(CC3)C
solubility soluble (Water solubility: 2.000 g/l at 19,5 °C - OECD Test Guideline 105 - completely)
sulfated ash ≤10%
technique(s) HPLC: suitable
  protein quantification: suitable
Application: Saponin from Quillaja bark has been used:
• to stain fertilized oocytes
• in the analysis of intracellular cytokine production
• to permeabilize dendritic cells
Biochem/physiol Actions: Potent hemolytic when injected i.v.; surfactant that enhances penetration of proteins and other macromolecules through cell membranes; it also has been used as an adjuvant for vaccines.
Biochem/physiol Actions: Saponins solubilize the low density lipoprotein (LDL) fraction of cholesterol in micelles, thus lowering their concentration. Saponin from Quillaja bark is used as a flavoring agent in food and beverages. This saponin has been shown to enhance immune-cell proliferation in vitro.
General description: Saponins are steroid or triterpenoid glycosides. They are biosurfactants that have several uses in the food and cosmetic industry.
Packaging: 10, 25 g in poly bottle
Preparation Note: Purified to remove low molecular weight contaminants 
UNSPSC 12161902

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