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Suplatast tosylate

SIGMA/S4701 - ≥98% (HPLC)

Synonym: (+/-)-[2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl] dimethylsulfonium p-toluenesulfonate; IPD-1151T; ST

CAS Number: 94055-76-2
Empirical Formula (Hill Notation): C16H26SNO4 · C7H7SO3
Molecular Weight: 499.64
MDL Number: MFCD00867604
Linear Formula: C16H26SNO4 · C7H7SO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S4701-50MG 50 mg
 $324.00
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assay ≥98% (HPLC)
color white to off-white
form powder
InChI 1S/C16H25NO4S.C7H8O3S/c1-4-20-11-14(18)12-21-15-7-5-13(6-8-15)17-16(19)9-10-22(2)3;1-6-2-4-7(5-3-6)11(8,9)10/h5-8,14,18H,4,9-12H2,1-3H3;2-5H,1H3,(H,8,9,10)
InChI key RYVJQEZJUFRANT-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cc1ccc(cc1)S([O-])(=O)=O.CCOCC(O)COc2ccc(NC(=O)CC[S+](C)C)cc2
solubility DMSO: >20 mg/mL
storage temp. room temp
Application: Suplatast tosylate may be used in immune-signaling studies.
Biochem/physiol Actions: Suplatast tosylate is a dimethylsulfonium compound downregulates the expression of histamine H1 receptor gene, suppresses the activity of histidine decarboxylase and regulates IL-4 mRNA. It inhibits the release of histamines and regulates the production of IgE.1,2 Suplatast tosylate is effective in the treatment of mild-to-moderate persistent asthma in children.3
Biochem/physiol Actions: Suplatast tosylate is an anti-allergy, cytokine modulator.
Packaging: 10, 50 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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