Somatotropin from human pituitary
SIGMA/S4776 - recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder
Synonym: Growth Hormone; STH
MDL Number: MFCD00081960
Product Type: Chemical
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| assay | ≥95% (SDS-PAGE) |
| biological source | human |
| drug control | Home Office Schedule 4.2 |
| form | lyophilized powder |
| impurities | endotoxin, tested |
| mol wt | predicted mol wt ~22 kDa |
| potency | 0.025-0.1 ng/mL cell proliferation using Nb2-11 cells per bioactivity ED50 |
| Quality Level | 200  |
| recombinant | expressed in E. coli |
| shipped in | ambient |
| solubility | PBS: 0.100 mL, clear, colorless (with 0.1% BSA ) |
| sterility | non-sterile |
| storage temp. | −20°C |
| UniProt accession no. | P01241  |
| P10912 |
| Application: | Somatotropin or growth hormone has been used to study the molecular interactions of ephrin type-A receptor 4 precursor (EphA4) with the growth hormone receptor. It has also been used to induce differentiation in mammary epithelial cell line HC11. |
| Biochem/physiol Actions: | Increases mass of most tissues by increasing cell number rather than cell size, mobilizes fat stores. |
| General description: | Somatotropin or growth hormone is a peptide hormone that is secreted by the anterior pituitary gland. It is essential for growth. The hormone increases muscle mass, reduces fat mass, helps in maintaining normal blood glucose levels and also promotes a balanced lipid profile. |
| Physical form: | Lyophilized from a 0.2 μm filtered solution in TBS (20 mM Tris, 0.15 M NaCl, pH 8.5) containing 50 μg of BSA per 1 μg of cytokine. |
| Preparation Note: | It is recommended that sterile PBS containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of no less than 10 μg/mL. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |