Anti-Sodium Channel, Brain Type I (α subunit) antibody produced in rabbit
SIGMA/S4936 - affinity isolated antibody, lyophilized powder
Synonym: Anti-BI; Anti-SP11I; Anti-Scna1
MDL Number: MFCD02097410
Product Type: Chemical
Immunohistochemistry Anti-Nav1.1: Cat. No. S4936: Immunohistochemical staining of Mouse cerebellum using Anti-Nav1.1 antibody (#ASC-001). A. The distribution of Nav1.1 (red) forms a band (arrows) in the molecular layer (Mol), close to the Purkinje cell bodies. B. Purkinje nerve cells are stained with Mouse Anti-Parvalbumin (green). C. Confocal merge of Nav1.1 and Parvalbumin.
Immunocytochemistry Anti-Nav1.1: Cat. No. S4936: Immunocytochemical staining of Paraformaldehyde-fixed and permeabilized Rat dorsal root ganglion (DRG) using Anti-Nav1.1 antibody, (1:200), followed by Goat Anti-Rabbit-AlexaFluor-555 secondary antibody. Nuclear staining of cells using the cell-permeable dye Hoechst 33342.
Immunoblotting Anti-NaV1.1: Cat. No. S4936: Western blot analysis of Rat brain membranes. Lanes 1. Anti-NaV1.1 antibody, (1:200). 2. Anti-NaV1.1 antibody, preincubated with the control peptide antigen.
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | lyophilized powder |
| Quality Level | 100  |
| species reactivity | rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: suitable using rat brain section |
| western blot: 1:200 using rat brain membranes | |
| UniProt accession no. | P04774  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Immunogen: | synthetic peptide corresponding to amino acids 465-481 of the α subunit of rat type I voltage-gated sodium channel (VGSC, SP11I) with additional N-terminal lysine and tyrosine, conjugated to KLH. The epitope corresponds to the sequence in the intracellular loop between the I and II domains of type I VGSC α subunit. Homology with human is identical. |
| Physical form: | Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 + H312 - H412 |
| Precautionary statements | P273 - P301 + P312 + P330 - P302 + P352 + P312 |
| Hazard Codes | T |
| Risk Statements | 24/25-52/53 |
| Safety Statements | 36/37-45-61 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |