Synonym: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)-4-(2,3-dihydro-1h-inden-2-yl)-piperazine
CAS Number: 146998-34-7
Empirical Formula (Hill Notation): C21H24N2O2
Molecular Weight: 336.43
MDL Number: MFCD00911672
Linear Formula: C21H24N2O2
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white |
| form |
solid |
| InChI |
1S/C21H24N2O2/c1-2-5-17-15-18(14-16(17)4-1)22-8-10-23(11-9-22)19-6-3-7-20-21(19)25-13-12-24-20/h1-7,18H,8-15H2 |
| InChI key |
QJPPEMXOOWNICQ-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
C1COc2c(O1)cccc2N3CCN(CC3)C4Cc5ccccc5C4 |
| solubility |
DMSO: ~6 mg/mL |
| |
H2O: insoluble |
| storage temp. |
2-8°C |
| Application: |
S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish. |
| Application: |
S15535 may be used in histamine 5-HT1A-medaited cell signaling studies. |
| Biochem/physiol Actions: |
Potent, orally active, partial 5-HT1A receptor agonist |
| Biochem/physiol Actions: |
S15535, a benzodioxane, is a selective but partial agonist of histamine serotonin 1A (5-HT1A) receptor. It activates presynaptic 5-HT1A receptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents. |
| Packaging: |
25 mg in glass bottle |
| Symbol |
 GHS09 |
| Signal word |
Warning |
| Hazard statements |
H400 |
| Precautionary statements |
P273 |
| Hazard Codes |
N |
| Risk Statements |
50 |
| Safety Statements |
61 |
| RIDADR |
UN 3077 9 / PGIII |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
