S15535
SIGMA/S5321 - ≥98% (HPLC), solid
Synonym: 1-
CAS Number: 146998-34-7
Empirical Formula (Hill Notation): C21H24N2O2
Molecular Weight: 336.43
MDL Number: MFCD00911672
Linear Formula: C21H24N2O2
Product Type: Chemical
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This image depicts S5321-25MG.
This image depicts S5321-25MG.
| assay | ≥98% (HPLC) |
| color | white |
| form | solid |
| InChI | 1S/C21H24N2O2/c1-2-5-17-1 |
| InChI key | QJPPEMXOOWNICQ-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | C1COc2c(O1)cccc2N3CCN(CC3 |
| solubility | DMSO: ~6 mg/mL |
| H2O: insoluble | |
| storage temp. | 2-8°C |
| Application: | S15535 has been used as a serotonin 1A receptor (5-HT1A) agonist in zebrafish. |
| Application: | S15535 may be used in histamine 5-HT1A-medaited cell signaling studies. |
| Biochem/physiol Actions: | Potent, orally active, partial 5-HT1A receptor agonist |
| Biochem/physiol Actions: | S15535, a benzodioxane, is a selective but partial agonist of histamine serotonin 1A (5-HT1A) receptor. It activates presynaptic 5-HT1A receptors and suppresses the release of hippocampal 5-HT. It acts as an anxiolytic agent and modulates the cholinergic and cognitive function in rodents. |
| Packaging: | 25 mg in glass bottle |
| Symbol |  GHS09 |
| Signal word | Warning |
| Hazard statements | H400 |
| Precautionary statements | P273 |
| Hazard Codes | N |
| Risk Statements | 50 |
| Safety Statements | 61 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |