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Sarpogrelate hydrochloride

SIGMA/S5451 - ≥98% (HPLC)

Synonym: Anplag; Butanedioic acid 1-[2-(dimethylamino)-1-[[2-[2-(3-methoxyphenyl)ethyl]phenoxy]methyl]ethyl] ester hydrochloride; MCI 9042; Succinic acid mono-(1-dimethylaminomethyl-2-(2-[2-(3-methoxyphenyl)et hyl]phenoxy)ethyl) ester hydrochloride

CAS Number: 135159-51-2
Empirical Formula (Hill Notation): C24H31NO6.HCl
Molecular Weight: 465.97
MDL Number: MFCD00887582
Linear Formula: C24H31NO6.HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S5451-5MG 5 mg
 $93.30
1/EA		 Add To Favorites
45-S5451-25MG 25 mg
 $252.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
form solid
InChI 1S/C24H31NO6.ClH/c1-25(2)16-21(31-24(28)14-13-23(26)27)17-30-22-10-5-4-8-19(22)12-11-18-7-6-9-20(15-18)29-3;/h4-10,15,21H,11-14,16-17H2,1-3H3,(H,26,27);1H
InChI key POQBIDFFYCYHOB-UHFFFAOYSA-N
Quality Level 100 
SMILES string Cl.COc1cccc(CCc2ccccc2OCC(CN(C)C)OC(=O)CCC(O)=O)c1
solubility deionized water: ≥5 mg/mL
storage condition desiccated
storage temp. room temp
Biochem/physiol Actions: Sarapogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist.
Biochem/physiol Actions: Sarapogrelate hydrochloride is a potent and selective 5-HT2A receptor antagonist. It exhibits analgesic effects in numerous animal studies.
General description: Sarpogrelate hydrochloride binds to the serotonin receptor (5-hydroxytryptamine, 5-HT2A). Its binding to 5-HT2A receptor inhibits thrombus formation and reduces platelet aggregation. Sarpogrelate hydrochloride has been used as an anti-atherosclerotic agent. It improves the endothelial function and may be useful for treating peripheral arterial disease. Use of sarpogrelate hydrochloride as 5-HT2A antagonist reduces urinary albumin levels in diabetic nephropathy.
Packaging: 5, 25 mg in glass bottle
Symbol GHS07GHS09  GHS07,GHS09
Signal word Warning
Hazard statements H302 - H400
Precautionary statements P273
Hazard Codes Xn,N
Risk Statements 22-50/53
Safety Statements 60-61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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