SW02
SIGMA/S5951
Synonym: 4-
CAS Number: 1010820-68-4
Empirical Formula (Hill Notation): C19H23BrN2O5
Molecular Weight: 439.30
MDL Number: MFCD17215960
Linear Formula: C19H23BrN2O5
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C19H23BrN2O5/c1-4-27-1 |
| InChI key | YFZRMRYVWWUQME-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | CCOC(=O)C1=C(C)N(CCCC(=O) |
| solubility | DMSO: ≥20 mg/mL |
| storage temp. | 2-8°C |
| Application: | SW02 may be used in Hsp70-mediated cell signaling studies. |
| Biochem/physiol Actions: | SW02 is a specific activator/agonist of Hsp70. |
| Biochem/physiol Actions: | SW02 is a specific activator/agonist of Hsp70. Hsp70 is of particular interest in diseases caused by protein misfolding, such as tau and Aβ in Alzheimer′s. SW02 increases Hsp70 ATPase activity, resulting in increased tau protein but not other disease-related proteins in cells. Hsp70 prevents aggregation of Aβ peptide, as shown by treatment with SW02. |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |