Staurosporine solution from Streptomyces sp.
SIGMA/S6942 - Ready Made Solution, 1 mM in DMSO (100 μg/214 μL)
Synonym: Antibiotic AM-2282
EC Number: 200-664-3
MDL Number: MFCD04041131
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S6942-200UL
| antibiotic activity spectrum | fungi |
| assay | >98% (HPLC) |
| concentration | 1 mM in DMSO (100 μg/214 μL) |
| mode of action | enzyme | inhibits |
| Quality Level | 300  |
| shipped in | wet ice |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Staurosporine solution from Streptomyces sp. was used to study the effect of PKC inhibition on signaling mediated by angiotensin II.3 It was used to induce cell death in Jurkat cells.4 |
| Biochem/physiol Actions: | Potent cell-permeable inhibitor of protein kinase C. Induces apoptosis in Jurkat cells. |
| Biochem/physiol Actions: | Potent inhibitor of phospholipid/calcium-depe |
| General description: | Chemical structure: indol derivative |
| Packaging: | 200 μL in glass bottle |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 188.6 °F - closed cup |
| Flash Point(C) | 87 °C - closed cup |
| Purity | >98% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |