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SB 657510

SIGMA/S7326 - ≥98% (HPLC)

Synonym: 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxy-benzenesulfonamide; SB-657510

CAS Number: 474960-44-6
Empirical Formula (Hill Notation): C19H22BrClN2O5S
Molecular Weight: 505.81
Linear Formula: C19H22BrClN2O5S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S7326-5MG 5 mg
 $171.00
1/EA		 Add To Favorites
45-S7326-25MG 25 mg
 $678.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to off-white
form powder
InChI 1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1
InChI key KQCZCINJGIRLCD-CYBMUJFWSA-N
originator GlaxoSmithKline
Quality Level 100 
SMILES string COc1cc(Br)c(cc1OC)S(=O)(=O)Nc2ccc(Cl)c(O[C@@H]3CCN(C)C3)c2
solubility DMSO: ≥30 mg/mL
storage temp. room temp
Application: SB 657510 may be used to study the urotensin II receptor-mediated signaling.
Biochem/physiol Actions: SB 657510 is a potent and selective urotensin-II (UT) receptor antagonist.
Biochem/physiol Actions: SB 657510 slows development of diabetes-associated atherosclerosis in mouse model of diabetes.1
Biochem/physiol Actions: SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension.
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H315 - H319 - H335
Precautionary statements P261 - P305 + P351 + P338
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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