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(S)-(−)-Sulpiride

SIGMA/S7771 - ≥98% (titration)

Synonym: (S)-5-Aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide; Levosulpiride

CAS Number: 23672-07-3
Empirical Formula (Hill Notation): C15H23N3O4S
Molecular Weight: 341.43
MDL Number: MFCD00055220
Linear Formula: C15H23N3O4S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-S7771-5G 5 g
$106.00
1/EA
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45-S7771-10G 10 g
$135.00
1/EA
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assay ≥98% (titration)
InChI 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
InChI key BGRJTUBHPOOWDU-NSHDSACASA-N
mp 183-186 °C (lit.)
originator Sanofi Aventis
Quality Level 100 
SMILES string CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
storage temp. 2-8°C
Application: (S)-(−)-Sulpiride was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels10 and on depression-like behavior in ovariectomized female rats.11
Biochem/physiol Actions: (S)-(−)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2 receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8 Since dopamine controls human sexual function, (S)-(−)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9
Biochem/physiol Actions: D2 dopamine receptor antagonist; antipsychotic.
Features and Benefits: This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 10 g in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (titration)
mp 183-186 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 12352200

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