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Succinylcholine chloride dihydrate

SIGMA/S8251 - 98.0-102.0%, solid

Synonym: Bis(trimethylammonioethyl) succinate chloride; Succinyldicholine dichloride

CAS Number: 6101-15-1
Empirical Formula (Hill Notation): C14H30Cl2N2O4 · 2H2O
Molecular Weight: 397.34
EC Number: 200-747-4
MDL Number: MFCD00150564
Linear Formula: [(CH3)3NCH2CH2OCOCH2]2Cl2 · 2H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8251-25G 25 g
 $125.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S8251-25G

 

assay 98.0-102.0%
color white
form solid
InChI 1S/C14H30N2O4.2ClH.2H2O/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;;;/h7-12H2,1-6H3;2*1H;2*1H2/q+2;;;;/p-2
InChI key FFSBEIRFVXGRPR-UHFFFAOYSA-L
originator Novartis
Quality Level 100 
SMILES string O.O.[Cl-].[Cl-].C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C
solubility H2O: complete 100 mg/ml, clear to slightly hazy, colorless
  H2O: soluble (unstable at pH > 9.)
Application: Succinylcholine chloride dehydrate was used to study the mechanism of gating of Cys loop receptors in Xenopus laevis.4,5
Biochem/physiol Actions: Cholinergic antagonist which induces a long-lasting depolarization of the acetylcholine neuron membrane; neuromuscular blocking agent.
Biochem/physiol Actions: Succinylcholine is a cholinergic antagonist and a neuromuscular blocking agent. It induces depolarization of acetylcholine receptors on the muscle membrane and efflux of potassium from the muscle that leads to hypokalemia in individuals with upregulated expression of acetylcholine receptors.3
Features and Benefits: This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 25 g in poly bottle
Preparation Note: Solutions may be stored for several days at 4 °C.
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H301
Precautionary statements P301 + P310
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 98.0-102.0%
UNSPSC 41116107

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