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(−)-Scopolamine methyl bromide

SIGMA/S8502 - ≥98% (HPLC), powder

Synonym: Hyoscine methyl bromide; Methscopolamine bromide

CAS Number: 155-41-9
Empirical Formula (Hill Notation): C18H24NO4 · Br
Molecular Weight: 398.29
EC Number: 205-844-5
MDL Number: MFCD00078560
Linear Formula: C18H24NO4 · Br
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8502-1G 1 g
 $89.70
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45-S8502-5G 5 g
 $341.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S8502-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S8502-5G

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C18H24NO4.BrH/c1-19(2)14-8-12(9-15(19)17-16(14)23-17)22-18(21)13(10-20)11-6-4-3-5-7-11;/h3-7,12-17,20H,8-10H2,1-2H3;1H/q+1;/p-1/t12-,13-,14-,15+,16-,17+;/m1./s1
InChI key CXYRUNPLKGGUJF-RAFJPFSSSA-M
optical activity [α]25/D −25°, c = 5 in H2O(lit.)
Quality Level 200 
SMILES string [Br-].[H][C@]12C[C@@H](C[C@]([H])([C@@]3([H])O[C@@]13[H])[N+]2(C)C)OC(=O)[C@H](CO)c4ccccc4
solubility H2O: 50 mg/mL
Application: (−)-Scopolamine methyl bromide was administered to rats to inhibit the peripheral cholinergic effects induced by pilocarpine.10,11
Biochem/physiol Actions: Competitive muscarinic acetylcholine receptor antagonist.
Biochem/physiol Actions: Scopolamine is an anti-muscarinic and cholinolytic alkaloid that inhibits parasympathetic-cholinergic system.7 The central effects include hallucinations, disorientation, restlessness and euphoria.8 Scopolamine disturb the stimulus detection performance in rats by interfering with the reticular cholinergic pathways.9
Disclaimer: Shelf-life of the powder is at least five years when stored at room temperature.
Packaging: 1, 5 g in poly bottle
Purity ≥98% (HPLC)
UNSPSC 12352116

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