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Sarsasapogenin

SIGMA/S8534 - ≥98%

Synonym: (25S)-Spirostan-3β-ol; Parigenin

CAS Number: 126-19-2
Empirical Formula (Hill Notation): C27H44O3
Molecular Weight: 416.64
EC Number: 204-776-3
MDL Number: MFCD00270414
Linear Formula: C27H44O3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8534-25MG 25 mg
 $154.00
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45-S8534-100MG 100 mg
 $445.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: S8534-25MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: S8534-100MG

 

application(s) metabolomics
vitamins, nutraceuticals, and natural products
assay ≥98%
InChI 1S/C27H44O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h16-24,28H,5-15H2,1-4H3/t16-,17-,18+,19-,20+,21-,22-,23-,24-,25-,26-,27+/m0/s1
InChI key GMBQZIIUCVWOCD-WWASVFFGSA-N
Quality Level 200 
SMILES string C[C@H]1CC[C@@]2(OC1)O[C@H]3C[C@H]4[C@@H]5CC[C@@H]6C[C@@H](O)CC[C@]6(C)[C@H]5CC[C@]4(C)[C@H]3[C@@H]2C
Application: Sarsasapogenin has been used as a synthetic saponin treatment to U-2 OS cells to test its effects in reducing osteosarcoma cell viability and down-regulating YAP and TAZ proteins.
Biochem/physiol Actions: Sarsasapogenin is a well-known multi-target directed ligand (MTDL) for Alzheimer′s disease. It elicits anti-inflammatory, antioxidant, anti-arthritis, anti-asthma, anti-amyloidogenic, neuroprotective, anti-depressant, and anti-cancer properties. SAR also improves learning and memory ability, loss of neurons in type-1 diabetic rats and protects against diabetic encephalopathy. It is also a therapeutic target for treating ulcerative colitis (UC). SAR as an anti-inflammatory agent improves insulin resistance and adipose tissue inflammation in high-fat diet (HFD)-fed mice.
General description: Sarsasapogenin also known as Sarsagenin or Parigenin, is a steroidal saponin and is the main constituent of Anemarrhena asphodeloides Bunge.
Packaging: 100 mg in poly bottle
Packaging: 25 mg in glass insert
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
UNSPSC 12352200

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