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SR 59230A

SIGMA/S8688 - ≥98% (HPLC), powder

Synonym: 3-(2-Ethylphenoxy)-1-[[(1S)-1,2,3,4-tetrahydronaphth-1-yl]amino]-(2S)-2-propanol oxalate salt

CAS Number: 174689-39-5
Empirical Formula (Hill Notation): C21H27NO2 · C2H2O4
Molecular Weight: 415.48
MDL Number: MFCD00940163
Linear Formula: C21H27NO2 · C2H2O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8688-5MG 5 mg
 $182.00
1/EA		 Add To Favorites
45-S8688-25MG 25 mg
 $660.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C21H27NO2.C2H2O4/c1-2-16-8-4-6-13-21(16)24-15-18(23)14-22-20-12-7-10-17-9-3-5-11-19(17)20;3-1(4)2(5)6/h3-6,8-9,11,13,18,20,22-23H,2,7,10,12,14-15H2,1H3;(H,3,4)(H,5,6)/t18-,20-;/m0./s1
InChI key XTBQNQMNFXNGLR-MKSBGGEFSA-N
originator Sanofi Aventis
Quality Level 100 
SMILES string OC(=O)C(O)=O.CCc1ccccc1OC[C@@H](O)CN[C@H]2CCCc3ccccc23
solubility DMSO: >10 mg/mL
  H2O: insoluble
Application: SR 59230A was used in the identification of β-adrenoceptors in rat aorta.3 It was tested as a potential therapeutic agent in improving cardiac function in rat model of heart failure.4
Biochem/physiol Actions: SR 59230A is a β3-adrenoceptor antagonist. It has high affinity for the β3 adrenoceptors occurring in human gut that affect the function of human colonic circular smooth muscle.1 It is reported that SR 59230A inhibits the Kir2.1-2.3 cardiac potassium channels.2
Features and Benefits: This compound is featured on the β-Adrenoceptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Sanofi Aventis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 12352200

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