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SFLLR-NH2 trifluoroacetate salt

SIGMA/S8701 - ≥95% (HPLC), powder

Synonym: L-Seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-Arginine amide trifluoroacetate salt; Ser-Phe-Leu-Leu-Arg-amide trifluoroacetate salt; Thrombin Receptor Activator for Peptide 5 (TRAP-5) trifluoroacetate salt

CAS Number: 1313730-13-0
Empirical Formula (Hill Notation): C30H51N9O6 · xC2HF3O2
Molecular Weight: 633.78 (free base basis)
MDL Number: MFCD18782167
Linear Formula: C30H51N9O6 · xC2HF3O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-S8701-1MG 1 mg
 $151.00
1/EA		 Add To Favorites

 

assay ≥95% (HPLC)
color white to off-white
form powder
InChI 1S/C30H51N9O6.C2HF3O2/c1-17(2)13-22(27(43)36-21(25(32)41)11-8-12-35-30(33)34)38-28(44)23(14-18(3)4)39-29(45)24(37-26(42)20(31)16-40)15-19-9-6-5-7-10-19;3-2(4,5)1(6)7/h5-7,9-10,17-18,20-24,40H,8,11-16,31H2,1-4H3,(H2,32,41)(H,36,43)(H,37,42)(H,38,44)(H,39,45)(H4,33,34,35);(H,6,7)/t20-,21-,22-,23-,24-;/m0./s1
InChI key UUNMFWMQJXBTAA-VHIJBDTGSA-N
Quality Level 100 
SMILES string OC(=O)C(F)(F)F.CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
solubility H2O: ≥2 mg/mL
storage temp. −20°C
Application: SFLLR-NH2 trifluoroacetate salt may be used in cell signaling and immunology studies.
Biochem/physiol Actions: SFLLR-NH2 is a PAR-1 (Protease-Activated Receptor) selective activating peptide, also known as Thrombin Receptor Activating Peptide 5 (TRAP-5). Protease-activated receptors (PARs) are present on various organs including, platelets, mast cell, gallblader, oesophagus etc, and regulate various physiological processes including human platelet aggregation, vascular contraction/relaxation, and an increase in endothelial permeability. Recent papers indicated that PAR′s are also involved in sensory processing and proliferation of astrocytes.
Biochem/physiol Actions: SFLLR-NH2 is a PAR-1 agonist peptide, Thrombin Receptor Activating Peptide (TRAP).
Packaging: 1 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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