Strychnine hydrochloride
SIGMA/S8753
CAS Number: 1421-86-9
Empirical Formula (Hill Notation): C21H22N2O2 · HCl
Molecular Weight: 370.87
EC Number: 215-826-9
MDL Number: MFCD00058174
Linear Formula: C21H22N2O2 · HCl
Product Type: Chemical
| InChI | 1S/C21H22N2O2.ClH/c24-18- |
| InChI key | VLXYTKMPCOQKEM-ZEYGOCRCSA |
| Quality Level | 100 ![]() |
| SMILES string | Cl.[H][C@@]12CC(=O)N3c4cc |
| Application: | Strychnine hydrochloride has been used as a glycine receptor antagonist in the retina for biophysiological functions. It has also been used to block glutamatergic, GABAergic and glycinergic receptors and gap junctions. |
| Biochem/physiol Actions: | Convulsant; glycine receptor antagonist not associated with the NMDA receptor. |
| Biochem/physiol Actions: | Strychnine is a potent convulsant, which is extracted from Strychnos nux vomica seeds. At high doses, the compound causes convulsions and ultimately death due to respiratory paralysis. Strychnine acts as a respiratory, circulatory and digestive stimulant. |
| Packaging: | 25 g in poly bottle |
| Symbol | ![]() GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H300 + H330 - H410 |
| Precautionary statements | P273 - P301 + P310 + P330 - P304 + P340 + P310 |
| Hazard Codes | T+,N |
| Risk Statements | 26/28-50/53 |
| Safety Statements | 13-28-45-60-61 |
| RIDADR | UN 1692PIHP2 6.1 / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352210 |



