SIB 1893
SIGMA/S9311 - >99%, solid
Synonym: [E]
CAS Number: 7370-21-0
Empirical Formula (Hill Notation): C14H13N
Molecular Weight: 195.26
MDL Number: MFCD02262120
Linear Formula: C14H13N
Product Type: Chemical
Representative of vacuum-sealed clear ampule packaging. Non-uniform tips are an inherent feature in this sealing process.
| assay | >99% |
| form | solid |
| InChI | 1S/C14H13N/c1-12-6-5-9-14 |
| InChI key | SISOFUCTXZKSOQ-ZHACJKMWSA |
| Quality Level | 100  |
| SMILES string | Cc1cccc(C=Cc2ccccc2)n1 |
| solubility | DMSO: 18 mg/mL |
| storage temp. | 2-8°C |
| Application: | SIB 1893 may be used in mGluR5 metabotropic glutamate receptor-mediated cell signaling studies. |
| Biochem/physiol Actions: | Selective and noncompetitive mGlu5 metabotropic glutamate receptor antagonist. |
| Biochem/physiol Actions: | SIB 1893 non-competitively inhibits glutamate-induced increase in Ca2+ at human metabotropic glutamate receptor 1 (hmGluR1).1 It also acts as a positive allosteric modulator of hmGluR4.2 |
| Features and Benefits: | This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 10 mg in ampule |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >99% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |