Sandoz 58-035
SIGMA/S9318 - >98% (HPLC), powder
Synonym: 3-
CAS Number: 78934-83-5
Empirical Formula (Hill Notation): C30H47NOSi
Molecular Weight: 465.79
MDL Number: MFCD00161339
Linear Formula: C30H47NOSi
Product Type: Chemical
| assay | >98% (HPLC) |
| color | white |
| form | powder |
| InChI | 1S/C30H47NOSi/c1-5-6-7-8- |
| InChI key | NBYATBIMYLFITE-UHFFFAOYSA |
| originator | Novartis |
| Quality Level | 100 ![]() |
| SMILES string | CCCCCCCCCC[Si](C)(C)CCC(= |
| solubility | DMSO: 16 mg/mL |
| H2O: insoluble | |
| storage temp. | 2-8°C |
| Application: | Sandoz 58-035 was used to induce simultaneous activation of unfolded protein response (UPR) and pattern recognition receptors (PRRs) in mouse peritoneal macrophages.3 |
| Biochem/physiol Actions: | Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. |
| Biochem/physiol Actions: | Sandoz 58-035 inhibits the accumulation of cholesteryl esters and inhibits the esterification of cholesterol by 95% in arterial smooth muscle cells in culture.1 It does not affect the triglyceride metabolism by the gut.2 |
| Features and Benefits: | This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41121801 |

