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Sandoz 58-035

SIGMA/S9318 - >98% (HPLC), powder

Synonym: 3-[Decyldimethylsilyl]-N-[2-(4-methylphenyl)-1-phenethyl]propanamide; SA 58-035

CAS Number: 78934-83-5
Empirical Formula (Hill Notation): C30H47NOSi
Molecular Weight: 465.79
MDL Number: MFCD00161339
Linear Formula: C30H47NOSi
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-S9318-5MG 5 mg
$217.00
1/EA
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45-S9318-25MG 25 mg
$896.00
1/EA
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assay >98% (HPLC)
color white
form powder
InChI 1S/C30H47NOSi/c1-5-6-7-8-9-10-11-15-23-33(3,4)24-22-30(32)31-29(28-16-13-12-14-17-28)25-27-20-18-26(2)19-21-27/h12-14,16-21,29H,5-11,15,22-25H2,1-4H3,(H,31,32)
InChI key NBYATBIMYLFITE-UHFFFAOYSA-N
originator Novartis
Quality Level 100 
SMILES string CCCCCCCCCC[Si](C)(C)CCC(=O)NC(Cc1ccc(C)cc1)c2ccccc2
solubility DMSO: 16 mg/mL
  H2O: insoluble
storage temp. 2-8°C
Application: Sandoz 58-035 was used to induce simultaneous activation of unfolded protein response (UPR) and pattern recognition receptors (PRRs) in mouse peritoneal macrophages.3
Biochem/physiol Actions: Acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor.
Biochem/physiol Actions: Sandoz 58-035 inhibits the accumulation of cholesteryl esters and inhibits the esterification of cholesterol by 95% in arterial smooth muscle cells in culture.1 It does not affect the triglyceride metabolism by the gut.2
Features and Benefits: This compound was developed by Novartis . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 41121801

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