Anti-RYK antibody produced in rabbit
SIGMA/SAB1300021 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-
Product Type: Chemical
Immunohistochemistry Anti-RYK Antibody: Cat. No. SAB1300021: RYK in human breast carcinoma tissue with Anti-RYK Antibody at 40 μg/mL.
Immunoblotting Anti-RYK Antibody: Cat. No. SAB1300021: RYK in HEK 293 cell line lysates either non-transfected (Lane 1) or transiently transfected (Lane 2) with Anti-RYK Antibody at 4.0 μg/mL.
Immunoblotting Anti-RYK Antibody: Cat. No. SAB1300021: RYK in Jurkat cell line lysates with Anti-RYK Antibody at 4.0 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_002949   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, rat, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| indirect ELISA: 1:1000 | |
| western blot: 1:100-1:500 | |
| UniProt accession no. | P34925 |
| General description: | RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists. |
| Immunogen: | RYK (165-201) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected within aa 150-200 of human RYK. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |