Anti-PYGM (C-term) antibody produced in rabbit
SIGMA/SAB1300187 - Ig fraction of antiserum, buffered aqueous solution
Synonym: Anti-Glycogen phosphorylase; Anti-Muscle form; Anti-
Product Type: Chemical
Immunohistochemistry Anti-PYGM (C-term) Antibody: Cat. No. SAB1300187: PYGM in human skeletal muscle tissue with Anti-PYGM (C-term) Antibody at 40 μg/mL.
Immunoblotting Anti-PYGM (C-term) Antibody: Cat. No. SAB1300187: PYGM in HEK 293 cell line lysates either non-transfected (Lane 1) or transiently transfected (Lane 2) with Anti-PYGM (C-term) Antibody at 4.0 μg/mL.
| antibody form | Ig fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_005600   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:1000 |
| western blot: 1:100-1:500 | |
| UniProt accession no. | P11217 |
| Biochem/physiol Actions: | PYGM catalyses and regulates the breakdown of glycogen to glucose-1-phosphate. Defects in PYGM are the cause of Glycogenosis type V/ glycogen storage disease type 5 (GSD5), also known as McArdle disease/ myophosphorylase deficiency, is an autosomal recessive disorder. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Glycogen phosphorylase, muscle associated (PYGM) encodes glycogen phosphorylase or myophosphorylase. In human chromosome, the gene PYGM is localized on 11q13.1. |
| Immunogen: | PYGM (NP_005600, 703-737) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PYGM. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |