Anti-Mouse Tlr2 (C-term) antibody produced in rabbit
SIGMA/SAB1300199 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-CD282 antigen; Anti-Toll-like receptor 2
Product Type: Chemical
Immunohistochemistry Anti-mouse TLR2 (C-term) Antibody: Cat. No. SAB1300199: mouse TLR2 in human hepatocarcinoma tissue with Anti-mouse TLR2 (C-term) Antibody at 40 at 40 μg/mL.
Immunohistochemistry Anti-mouse TLR2 (C-term) Antibody: Cat. No. SAB1300199: mouse TLR2 in human lung carcinoma tissue with Anti-mouse TLR2 (C-term) Antibody at 40 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_036035   |
| Quality Level | 200 |
| shipped in | dry ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| indirect ELISA: 1:1000 | |
| western blot: 1:100-1:500 | |
| UniProt accession no. | Q9QUN7 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | TLR2 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. TLR2 is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. |
| Immunogen: | TLR2 (NP_036035, 725-760) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of mouse TLR2. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |