Anti-SPPL2a (N-term) antibody produced in rabbit
SIGMA/SAB1300346 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-IMP3; Anti-SPP-like 2A protein; Anti-SPPL2a protein; Anti-Signal peptide peptidase-like 2A; Intramembrane protease 3
Product Type: Chemical
Immunohistochemistry Anti-SPPL2A (N-term) Antibody: Cat. No. SAB1300346: SPPL2A in human placenta tissue with Anti-SPPL2A (N-term) Antibody at 40 μg/mL.
Immunoblotting Anti-SPPL2A (N-term) Antibody: Cat. No. SAB1300346: SPPL2A in Jurkat cell line lysates with Anti-SPPL2A (N-term) Antibody at 4.0 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_116191   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| indirect ELISA: 1:1000 | |
| western blot: 1:100-1:500 | |
| UniProt accession no. | Q8TCT8 |
| General description: | By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus. |
| Immunogen: | SPPL2A (Q8TCT8, 12-42) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human SPPL2a. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |