Anti-PRKAG1 (center) antibody produced in rabbit
SIGMA/SAB1300373 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-γ-1 subunit; Anti-5′-AMP-activated protein kinase; Anti-AMPK γ-1 chain; Anti-AMPKg
Product Type: Chemical
Immunohistochemistry Anti-PRKAG1 (Center) Antibody: Cat. No. SAB1300373: PRKAG1 in human testis tissue with Anti-PRKAG1 (Center) Antibody at 40 μg/mL.
Immunohistochemistry Anti-PRKAG1 (Center) Antibody: Cat. No. SAB1300373: PRKAG1 in human breast carcinoma tissue with Anti-PRKAG1 (Center) Antibody at 40 μg/mL.
Immunoblotting Anti-PRKAG1 (Center) Antibody: Cat. No. SAB1300373: PRKAG1 in mouse heart tissue lysates with Anti-PRKAG1 (Center) Antibody at 4.0 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_002724   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human, mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| indirect ELISA: 1:1000 | |
| western blot: 1:100-1:500 | |
| UniProt accession no. | P54619 |
| General description: | PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. |
| Immunogen: | PRKAG1 (AAKG_HUMAN, 270-306) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PRKAG1. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |