Anti-Epstein-Barr BGLF4 Kinase (N-term) antibody produced in rabbit
SIGMA/SAB1300446 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-
Product Type: Chemical
Immunohistochemistry Anti-Epstein-Barr BGLF4 Kinase (N-term) Antibody: Cat. No. SAB1300446: Epstein-Barr BGLF4 Kinase in human hepatocarcinoma tissue with Anti-Epstein-Barr BGLF4 Kinase (N-term) Antibody at 40 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | YP_401688   |
| Quality Level | 200 |
| shipped in | dry ice |
| species reactivity | Epstein-Barr virus |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:1000 |
| UniProt accession no. | P13288 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Epstein-Barr BGLF4 plays many key roles by phosphorylating several proteins including the viral DNA processivity factor BMRF1, EBNA1 or EBNA2. It is required for efficient lytic DNA replication and release of nucleocapsids from the nucleus. This protein contributes to the compaction of host cell chromatin in cells undergoing lytic replication, presumably by phosphorylating the host condensin complex and host TOP2A. BGLF4 induces disassembly of the nuclear lamina by phosphorylating with host LMNA, and phosphorylates substrates involved in capsid assembly and DNA packaging. It facilitates the switch from latent to lytic DNA replication by down-regulating EBNA1 replication function. This protein phosphorylates the viral immediate-early protein BZLF1. |
| Immunogen: | BGL (1-30) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of Epstein-Barr BGLF4 Kinase. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |