Anti-KLF4 antibody produced in rabbit
SIGMA/SAB1300678 - saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
Synonym: Anti-EZF; Anti-GKLF; Anti-Kruppel-like factor 4
Product Type: Chemical
Immunoblotting Anti-KLF4 Antibody: Cat. No. SAB1300678: KLF4 in HEK 293 cell line lysates with Anti-KLF4 Antibody at 4.0 μg/mL.
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_004226.3   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:1000 |
| western blot: 1:100-1:500 | |
| UniProt accession no. | O43474 |
| Biochem/physiol Actions: | Krüppel-like factor 4 (KLF4) is involved in cell growth, proliferation and differentiation in the colon. It is down-regulated in both mouse and human colonic adenomas. The protein has been implicated as a tumor suppressor in the gut, whereas in breast cancer, KLF4 is an oncogene. It is also involved in reprogramming differentiated cells into pluripotent stem cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Krüppel-like factor 4 (KLF4) is a transcription factor. It can act both as a transcriptional activator or repressor. The gene encoding this protein is localized on human chromosome 9q31.2. |
| Immunogen: | KLF4 (NP_004226.3, ) This antibody is generated from rabbits immunized with a his tag recombinant protein of human KLF4. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |