Anti-CYP26A1 (center) antibody produced in rabbit
SIGMA/SAB1300686 - saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
Synonym: Anti-CYP26A1; Cytochrome P450, family 26, subfamily A, polypeptide 1 (Cytochrome P450, family 26, subfamily A, polypeptide 1, isoform CRA_b)
Product Type: Chemical
Immunohistochemistry Anti-CYP26A1 (Center) Antibody: Cat. No. SAB1300686: CYP26A1 in human brain tissue with Anti-CYP26A1 (Center) Antibody at 40 μg/mL.
Immunofluorescence Anti-CYP26A1 (Center) Antibody: Cat No. SAB1300686: CYP26A1 in HeLa cells with Anti-CYP26A1 (Center) Antibody at 4 μg/mL.
Immunoblotting Anti-CYP26A1 (Center) Antibody: Cat. No. SAB1300686: CYP26A1 in NCI-H460 cell line lysates with Anti-CYP26A1 (Center) Antibody at 4.0 μg/mL.
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_000774   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | indirect ELISA: 1:1000 |
| western blot: 1:100-1:500 | |
| UniProt accession no. | O43174 |
| Biochem/physiol Actions: | Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is a retinoic acid (RA) degrading enzyme. It plays a vital role in RA metabolism. CYP26A1 has an essential role in the correct anteroposterior patterning and the generation of migratory cranial neural crest cells in the developing mammalian brain. Mutations in the gene is associated with the pathogenesis of optic nerve aplasia (ONA). |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Cytochrome P450 family 26 subfamily A member 1 (CYP26A1) is encoded by the gene mapped to human chromosome 10q23.33. The previously assigned protein identifier Q5VXI0 has been merged into O43174. Full details can be found on the UniProt database. |
| Immunogen: | CYP26A1 (NP_000774, 123-157) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CYP26A1. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |