Anti-CYP2R1 (center) antibody produced in rabbit
SIGMA/SAB1300955 - saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
Synonym: Anti-CYP2R1; Anti-Cytochrome P450 2R1; Anti-Vitamin D 25-hydroxylase
Product Type: Chemical
Immunohistochemistry Anti-CYP2R1 (Center) Antibody: Cat. No. SAB1300955: CYP2R1 in human brain tissue with Anti-CYP2R1 (Center) Antibody at 40 μg/mL.
Immunoblotting Anti-CYP2R1 (Center) Antibody: Cat. No. SAB1300955: CYP2R1 in mouse liver tissue lysates with Anti-CYP2R1 (Center) Antibody at 4.0 μg/mL.
Immunoblotting Anti-CYP2R1 (Center) Antibody: Cat. No. SAB1300955: CYP2R1 in NCI-H460 cell line lysates with Anti-CYP2R1 (Center) Antibody at 4.0 μg/mL.
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_078790   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| indirect ELISA: 1:1000 | |
| western blot: 1:100-1:500 | |
| UniProt accession no. | Q6VVX0 |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | CYP2R1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in CYP2R1 gene has been associated with selective 25-hydroxyvitamin D deficiency. |
| Immunogen: | CYP2R1 (NP_078790, 157-190) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human CYP2R1. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |