Anti-ALOX5AP (center) antibody produced in rabbit
SIGMA/SAB1300959 - saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution
Synonym: Anti-ALOX5AP; Anti-Arachidonate 5-
Product Type: Chemical
Immunohistochemistry Anti-ALOX5AP (Center) Antibody: Cat. No. SAB1300959: ALOX5AP in human lung carcinoma tissue with Anti-ALOX5AP (Center) Antibody at 40 μg/mL.
Immunoblotting Anti-ALOX5AP (Center) Antibody: Cat. No. SAB1300959: ALOX5AP in K562 cell line lysates with Anti-ALOX5AP (Center) Antibody at 4.0 μg/mL.
| antibody form | saturated ammonium sulfate (SAS) precipitated |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| NCBI accession no. | NP_001620   |
| Quality Level | 100 |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | immunohistochemistry: 1:50-1:100 |
| indirect ELISA: 1:1000 | |
| western blot: 1:100-1:500 | |
| UniProt accession no. | P20292 |
| General description: | ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. |
| Immunogen: | ALOX5AP (NP_001620, 91-127) This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human ALOX5AP. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |