ANTI-MOUSE NLRP6 (CENTER) antibody produced in rabbit
SIGMA/SAB1302240 - IgG fraction of antiserum, buffered aqueous solution
Synonym: LRR and PYD domains-containing protein 6; NACHT; Nalp6; Nlrp6; Pypaf5
Product Type: Chemical
Immunoblotting Anti-Mouse Nlrp6 (Center): Cat. No. SAB1302240: Mouse Nlrp6 Antibody western blot analysis in mouse heart tissue lysates (35 μg/lane).
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 97402 Da |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | mouse |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1:1000 |
| UniProt accession no. | Q91WS2  |
| Biochem/physiol Actions: | NLR family, pyrin domain containing 6 (NLRP6) has a role in innate immunity. It also maintains intestinal homeostasis by modulating autophagy and mucus secretion. Loss of NLRP6 has been shown to hinder the production of interleukin-18 (IL-18) and enhance susceptibility to epithelial-induced injury in rats. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | NLR family, pyrin domain containing 6 (NLRP6) maybe part of the inflammasome. It belongs to the Nod-like receptor family and is expressed in intestinal epithelial cells. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |