ANTI-IL17RB (CENTER) antibody produced in rabbit
SIGMA/SAB1303013 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Cytokine receptor CRL4; EVI27; IL-17 receptor B; IL-17 receptor homolog 1; IL-17B receptor; IL-17RB; IL-17Rh1; IL17BR; IL17RB; IL17Rh1; Interleukin-17 receptor B; Interleukin-17B receptor; UNQ2501/PRO19612
Product Type: Chemical
Immunohistochemistry IL17RB (Center): Cat. No. SAB1303013: IL17RB in Human colon carcinoma tissue with IL17RB antibody (Center) at 5 μg/mL.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 55885 Da |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: 1:10-1:50 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:250-1:500 | |
| UniProt accession no. | Q9NRM6  |
| Application: | Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below. Western Blotting (1 paper) |
| Biochem/physiol Actions: | Interleukin 17 receptor B (IL-17RB) might be considered in thyroid cancer therapy as a potential therapeutic target. IL17RB exhibits much efficient binding avidity to interleukin 17 E (IL17E). IL-17RB is overexpressed in pancreatic, gastric, and prostate cancers. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Interleukin 17 receptor B (IL-17RB) belongs to the IL-17 receptor family. IL17RB, the receptor for interleukin 17 B (IL17B) is expressed at a high level in the liver, kidney, and other peripheral organs. It is also expressed in memory and effector T lymphocytes. IL17RB gene is located on human chromosome 3p21.1. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |