ANTI-HSD17B2 (CENTER) antibody produced in rabbit
SIGMA/SAB1303130 - IgG fraction of antiserum, buffered aqueous solution
Synonym: 17-beta-HSD 2; 17-
Product Type: Chemical
Immunohistochemistry HSD17B2 (Center): Cat. No. SAB1303130: HSD17B2 in Human prostate carcinoma tissue with HSD17B2 antibody (Center) at 5 μg/mL.
Immunoblotting Anti-HSD17B2 (Center): Cat. No. SAB1303130: Western blot analysis of HSD17B2 Antibody (Center) in MDA-MB435 cell line lysates (35 μg/lane).
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 42785 Da |
| Quality Level | 100  |
| shipped in | wet ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: 1:10-1:50 |
| immunohistochemistry: 1:10-1:50 | |
| western blot: 1:1000 | |
| UniProt accession no. | P37059  |
| Application: | ANTI-HSD17B2 (CENTER) antibody produced in rabbit is suitable for flow cytometry (1:10-1:50), immunohistochemistry (1:50-1:100), and western blot: 1:250-1:500. |
| Biochem/physiol Actions: | HSD17B2 (Hydroxysteroid 17-β dehydrogenase 2) is highly involved in the synthesis and metabolism of steroid hormones. It maintains the intracellular concentration of biologically active steroid hormones in a wide range of male and female human tissues. It catalyzes the interconversion of testosterone and androstenedione as well as estradiol and estrone through 17-β HSD activities. HSD17B2 also exhibits 20α-HSD activity toward 20α-dihydroprogesterone. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | HSD17B2 (Hydroxysteroid 17-β dehydrogenase 2) is a member of the short chain alcohol dehydrogenase superfamily expressed in non-steroidogenic human embryonic kidney cells. |
| Physical form: | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |