ANTI-BECLIN 1 antibody produced in rabbit
SIGMA/SAB1306484 - IgG fraction of antiserum, buffered aqueous solution
Synonym: BECN1; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; GT197; Protein GT197
Product Type: Chemical
Immunoblotting Anti-Beclin 1 : Cat. No. SAB1306484: Western blot analysis of Anti-hBECN1-E225 Pab in 293 cell line lysates transiently transfected with the BECN1 gene (2 μg/lane).
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| mol wt | 51896 Da |
| NCBI accession no. | NP_003757.1   |
| Quality Level | 100 |
| shipped in | wet ice |
| species reactivity | mouse, human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | flow cytometry: 1:10-1:50 |
| immunohistochemistry: 1:50-1:100 | |
| western blot: 1:1000 | |
| UniProt accession no. | Q14457 |
| Application: | ANTI-BECLIN 1 antibody produced in rabbit has been used for Western blotting. |
| Biochem/physiol Actions: | Beclin 1 (BECN1) or GT197 acts as an initiator of autophagy and is vital in the early stages of autophagosome formation. It has a role in various tumors and cancers. BECN1 is a component of the phosphatidylinositol-3-ki |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Beclin 1 (BECN1) or GT197 is a tumor suppressor gene. It is a 450 amino-acid protein having three domains. The gene encoding BECN1 is localized on human chromosome 17q21. |
| Physical form: | Supplied in PBS with 0.09% (W/V) sodium azide |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |