Anti-CYP3A4 antibody produced in rabbit
SIGMA/SAB1400065 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-CP33; Anti-CP34; Anti-CYP3A; Anti-CYP3A3; Anti-HLP; Anti-MGC126680; Anti-NF-25; Anti-P450C3; Anti-P450PCN1
MDL Number: MFCD01633033
Product Type: Chemical
Western Blotting CYP3A4 rabbit polyclonal antibody. Western Blot analysis of CYP3A4 expression in HepG2.
Western Blotting Western Blot analysis of CYP3A4 expression in transfected 293T cell line by CYP3A4 polyclonal antibody. Lanes Lane 1: CYP3A4 transfected lysate (57.30 kDa). Lane 2: Non-transfected lysate.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| UniProt accession no. | P08684  |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. (provided by RefSeq) |
| Immunogen: | CYP3A4 (AAI01632.1, 1 a.a. ~ 503 a.a) full-length human protein. Sequence MALIPDLAMETWLLLAVSLVLLYLY |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |