Anti-SEPT5 antibody produced in mouse
SIGMA/SAB1400216 - IgG fraction of antiserum, buffered aqueous solution
Synonym: Anti-CDCREL; Anti-CDCREL-1; Anti-CDCREL1; Anti-H5; Anti-PNUTL1
MDL Number: MFCD00675556
Product Type: Chemical
Western Blotting Western Blot analysis of SEPT5 expression in transfected 293T cell line by SEPT5 polyclonal antibody. Lanes Lane 1: SEPT5 transfected lysate (40.59 kDa). Lane 2: Non-transfected lysate.
Western Blotting SEPT5 polyclonal antibody. Western Blot analysis of SEPT5 expression in human liver.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | mouse |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 100  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 1 μg/mL |
| General description: | This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Two transcripts of this gene, a major one of 2.2 kb and a minor one of 3.5 kb, have been observed. The 2.2 kb form results from the utilization of a non-consensus polyA signal (AACAAT). In the absence of polyadenylation from this imperfect site, the consensus polyA signal of the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) is used, resulting in the 3.5 kb transcript. An alternatively spliced transcript variant with a different 5′ end has also been identified, but its full-length nature has not been completely determined. (provided by RefSeq) |
| Immunogen: | SEPT5 (NP_002679.2, 1 a.a. ~ 369 a.a) full-length human protein. Sequence MSTGLRYKSKLATPEDKQDIDKQYV |
| Physical form: | Solution in phosphate buffered saline, pH 7.4 |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |